| 1850 | The total endowment at this time was $180,489.59. |
| 1850 | Yale enrollment was 555. |
| 1851 | Graduates of Yale College 1702-1851 numbered 6,093. |
| Jul 27 1852 | Degree of Bachelor of Philosophy authorized by the Corporation to be given in the Department of Philosophy and the Arts. |
| 1852 | Organization of a School of Engineering under Professor William Augustus Norton. |
| 1852 | First award of the DeForest Prize; established for the Senior who "shall write and pronounce an English oration in the best manner." |
| 1854 | The name Yale Scientific School applied to the School of Applied Chemistry and School of Engineering. |
| 1854 | Yung Wing graduated, the first Chinese student to graduate from an American college. |
| 1856 | Fund-raising pamphlets issued: Proposed Plan for a complete organization of the School of Science and Appeal in Behalf of the Yale Scientific School, with an Appendix. |
| 1857 | Cortland Van Renssalaer Creed graduated from the medical school, the first African American graduate of Yale. |
| Oct 30 1858 | Joseph E. Sheffield, Esq., conveyed to the President and Fellows of Yale College a deed to property on the northeast corner of Grove and Prospect streets for the use of the Scientific School. His gifts and bequests for equipment and endowment ultimately exceeded $1,000,000. |
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